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Z718211
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Discovering Neurons: The Experimental Basis of Neuroscience
| ISBN-10: | 0-87969-455-6 |
| ISBN-13: | 978-0-87969-455-5 |
Description
| General description | Discovering Neurons is a collection of investigative laboratory experiments designed for the advanced undergraduate and the first or second year graduate student. In its three major sections, neurons are studied as: individual cells, including topics such as intracellular recording, immunocytochemistry and HPLC forming connections, with experiments on tract tracing, information coding and LTP, among others as coordinators of behavior, through approaches such as pharmacology, lesioning and ethology. The fourth section focuses on techniques applicable to several experiments in the collection, including electrophysiology recording, surgery, anesthetics and staining methods. The experiments introduce students to the techniques used in today's leading neuroscience research labs. They have been thoroughly tested in the student laboratory and are written and designed to be easily integrated into existing neuroscience courses of any length or emphasis. This is a unique volume that is an important resource for all teachers of neuroscience. |
Properties
| publication info | C. Paul & B. Beltz, ed., Cold Spring Harbor Laboratory Press, 1997, 420 pp., comb bound |
| availability | available only in EU |
| not available in ROW | |
| not available in USA and Canada |
Table Of Contents
| Table of Contents | Introduction SECTION 1 Neurons as Cells Laboratory 1 Studying the Neuron Using Intracellular Recording: The Action Potential and Neuronal Anatomy Laboratory 2 An Introduction to Neurochemistry: Acetylcholinesterase Assay Laboratory 3 Immunocytochemical Localization of Neuronal Transmitters: Two Methods for Identifying Neurotransmitters In Situ Laboratory 4 Pharmacological Manipulation of Catecholamine Neurochemical Levels: An Analysis Using HPLC Laboratory 5 Ca-activated Chloride Conductance in Xenopus Oocytes: Introduction to Methods of Molecular Neurobiology SECTION 2 Neurons Forming Connections Laboratory 1 Synaptic Transmission and Synaptic Plasticity: The Neuromuscular Junction of the Crayfish Laboratory 2 Tracing Neural Connections: Thalamo-cortical Interconnections in the Mammalian Somatosensory System Laboratory 3 Information Coding and Receptive Fields: Properties of Mammalia Neurons Recorded in Rat Thalamus Laboratory 4 Field Potential Recording in the Hippocampal Slice Laboratory 5 Long-term Potentiation: Stimulating and Recording in the Hippocampus of an Anesthetized Rat SECTION 3 Neurons Coordinating Behavior Laboratory 1 Observational Methods Used to Assess Behavior Laboratory 2 Neuropharmacology: Comparison of Behavioral Response in Infant and Adult Rats after Drug Administration Laboratory 3 Chronic Recording from Rat Brain: Hippocampal Theta Rhythm Laboratory 4 Effects of Lesion on Spatial and Nonspatial Learning Laboratory 5 Control of the Ovulatory Cycle and Sexual Behavior in the Syrian Hamster SECTION 4 Techniques Protocol 1 Using Electrophysiological Equipment Protocol 2 Surgery Procedures Protocol 3 Perfusion and Sectioning Protocol 4 Staining: Golgi, Nissl, Acethycholinesterase, and Choline Acetyltransferase APPENDICES Appendix 1: Sources of Equipment Appendix 2: Addresses of Suppliers Appendix 3: Use of Animals in Experiments |
